Enclomephine is a medication commonly used to treat low libido and sexual dysfunction. It works by increasing levels of dopamine and norepinephrine in the brain, which can help improve sexual desire and arousal. However, some individuals may experience a decrease in libido while taking enclomephine. If you notice a drop in your libido while on this medication, it may be necessary to increase your dosage.
If future research finds that both clomiphene and enclomiphene are equally effective in treating secondary male hypogonadism, clomiphene may be recognized as the best option of the three medications due to its lower cost. The study points out that it is unknown if enclomiphene is superior to clomiphene for treating secondary male hypogonadism because the two medications have not been directly compared to one another. Although enclomiphene produces many benefits with PCT, it also comes with side effects. Men who take it for post cycle therapy may develop acne, an increased sex drive, and potentially, a temper. Enclomiphene may be a suitable alternative treatment for men who cannot use testosterone replacement therapy. Although treatments are generally well tolerated and safe for use, it is essential to speak with your doctor to determine if this treatment is right for you.
Reasons for Decreased Libido
There are several reasons why your libido may drop while taking enclomephine. These can include:
- Changes in hormone levels
- Stress or anxiety
- Side effects of the medication
Enclomiphene citrate is proposed for the treatment of some men who have secondary hypogonadism, especially that caused by dysfunctional, but reversible hypothalamus/pituitary activity. These men present with low total testosterone and low or inappropriately normal gonadotropin levels (LH and FSH). To our knowledge, there are no clinical studies directly comparing the effects of CC and EC on serum testosterone levels or semen parameters in men.
Or, honestly, just google Enclomiphene and take a look at the studies and modes of actions. I also take a fair amount of vitamins to keep free test elevated and SHBG levels low. That being said, I plan on dropping back down to 6.25 mg ED of enclomiphene. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Low libido reduces the drive that men have to pursue sex and can lead to infrequent sexual encounters, also reducing the potential for pregnancy. If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. Researchers believe that people can increase levels of this feel-good chemical through activities such as exercising, eating endorphin-releasing foods like dark chocolate, and tapping into their sense of humor.
Enclomiphene “antagonizes” negative feedback on gonadotropin-releasing hormone (GnRH). Additionally, patients who have a history of liver disease, uncontrolled adrenal or thyroid dysfunction, or a known allergic reaction to enclomiphene or clomiphene should avoid the medication. Initial studies were concerned with a few more serious health reactions including venous thromboembolisms, but the study incidences were in the “very low” category and have not been considered a side effect of the medication.
Additionally, there was also an increase in FSH as has been shown previously for clomiphene in healthy men [24]. Transdermal testosterone, by contrast, significantly suppressed LH after as little as 2 weeks of administration. The relatively higher levels of FSH, compared with those of LH, suggest that sperm count was being stimulated. Of the men who received treatment for more than three years, 88 percent reached normal testosterone levels, 77 percent noticed improvement in symptoms, and eight percent experienced side effects. There were no significant differences in results between patients treated for more than three years and patients treated for three or fewer years. The study concluded that clomiphene citrate causes few side effects and is safe and effective in treating male hypogonadism long-term.
Increasing Dosage
If you suspect that your decreased libido is due to enclomephine, it is important to speak with your healthcare provider before adjusting your dosage. They may recommend increasing your dosage gradually to see if it helps improve your libido.
Frequently Asked Questions
Q: Can I increase my enclomephine dosage on my own?
If you feel a “severe drop,” you should take 100 milligrams of enclomiphene per day. Some people choose to split doses in half and take half in the afternoon and half in the morning. Testosterone most often shuts down when androgens increase in the blood.
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Q: How long does it take for an increased dosage to take effect?
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Overall, if you experience a drop in libido while taking enclomephine, it may be necessary to increase your dosage under the guidance of a healthcare provider. By monitoring your symptoms and working closely with your provider, you can find the right dosage to help improve your libido and overall sexual satisfaction.
